Sildenafil Mesylate (CAS No.: 131543-23-2) yog cov organic compound nrog cov mis molecular C28H30N2O6S, molecular hnyav ntawm 522.6126, thiab tus nqi logp ntawm 5.12230. Raws li ib qho kev xaiv inhibitor ntawm phosphodiesterase type 5 (PDE5) tshwj xeeb rau cyclic guanosine monophosphate, nws txhawb nqa erection los ntawm kev so ntawm cov leeg nqaij. Piv nrog rau sildenafil citrate, mesylate muaj qhov zoo ntawm cov tshuaj qis dua, cov kev mob tshwm sim tsawg dua, thiab cov dej zoo dua thiab ethanol solubility.
Dosage thiab Administration
Rau cov neeg mob feem ntau, cov koob tshuaj pom zoo yog 120 mg, noj raws li xav tau kwv yees li 1 teev ua ntej kev sib deev, nrog rau kev sib deev xav tau tom qab kev tswj hwm. Txawm li cas los xij, nws tuaj yeem noj txhua lub sijhawm hauv 0.5-4 teev ua ntej kev sib deev. Raws li kev ua tau zoo thiab kev kam rau siab, koob tshuaj txhua hnub yuav raug hloov mus rau nruab nrab ntawm 150 mg, tab sis yuav tsum tsis txhob noj ntau dua ib hnub.
- Kev noj tshuaj rau lub raum tsis txaus: Kev pom zoo pib koob tshuaj rau cov neeg mob lub raum tsis ua haujlwm hnyav (thaum creatinine tshem tawm tsawg dua lossis sib npaug li 30 ml / min, AUC thiab cmax yuav luag ob npaug) yog 25 mg.
- Kev noj tshuaj rau lub siab tsis txaus: Qhov pom zoo pib koob tshuaj rau cov neeg mob uas muaj lub siab tsis zoo (xws li mob siab, qhov twg AUC thiab cmax nce 84% thiab 47%, feem) yog 80 mg.
Cov khoom specifications thiab cov khoom
- CAS Nr . 131543-23-2
- Cov mis mos molecular: C28H30N2O6S
- Molecular Luj: 522.6126
- Purity: 99%
- Cov tsos mob: Dawb hmoov
- Txoj Kev Tshawb Nrhiav: Kev ua haujlwm siab spectroscopy
- Txheem: USP
Kev tsim khoom thiab kev siv:
Sildenafil mesylate kuj yog ib qho kev xaiv inhibitor ntawm cyclic guanosine monophosphate (cGMP) - tshwj xeeb phosphodiesterase hom 5 (PDE5), uas tuaj yeem so cov leeg nqaij leeg thiab ua tiav erection sai. Sildenafil mesylate siv cov nyhuv hauv 52% ntawm cov neeg mob hauv 30 feeb ntawm kev tswj hwm thiab hauv 82% hauv 1 teev. Nws ib nrab -lub neej yog 5 mus rau 12 teev. Cov koob tshuaj pom zoo rau sildenafil mesylate yog 50-100 mg, nrog 120 mg pom zoo rau cov neeg ntawm East Asian qhovntsej thiaj tsis mob. Piv nrog rau sildenafil citrate, sildenafil mesylate muaj qhov zoo xws li kev siv tshuaj tsawg, txo qis kev phiv, thiab solubility hauv dej thiab ethanol.
Vim li cas thiaj xaiv peb
Peb muab kev pabcuam ncaj qha; guaranteeing kev sib tw nqi thiab zoo. Peb tuaj yeem npaj cov khoom xa tuaj tib yam -hnub xa khoom tom qab xaj, ua kom cov khoom zoo thiab kev xa khoom ruaj khov, tso cai rau kev sib koom tes muaj txiaj ntsig.
