Theophylline (CAS No. 58-55-9) yog cov organic compound nrog cov tshuaj formula C7H8N4O2. Nws txo cov leeg leeg thiab nthuav dav cov hlab ntsha; nws txhawb kev tso tawm ntawm endogenous adrenaline thiab noradrenaline, so kom txaus cov leeg nqaij; thiab nws inhibits qhov tso tawm ntawm calcium ions los ntawm endoplasmic reticulum ntawm cov nqaij ntshiv, txo intracellular calcium ion concentration thiab yog li ua tau ib tug pa dilation nyhuv. Theophylline muaj zog so ntawm cov leeg nqaij, tab sis nws tsis muaj zog dua li - receptor agonists.
Cov lus qhia
1. Siv rau bronchial hawb pob, mob ntsws ntsws, mob ntsws asthmatic, obstructive emphysema, thiab lwm yam, los txo cov tsos mob hawb pob. Nws kuj tseem tsim nyog rau cov tsos mob ntawm bronchospasm cuam tshuam nrog mob bronchitis thiab emphysema.
2. tuaj yeem siv rau cov neeg mob uas muaj mob hawb pob, mob plawv edema, thiab mob plawv tsis ua haujlwm.
3. kuj tseem siv tau rau cov neeg mob biliary colic.
Dosage thiab Administration
Qhov ncauj: 0.1-0.2 g / koob, ob zaug ib hnub; Qhov siab tshaj plaws koob tshuaj: 0.3 g / koob, 1 g / hnub.
Tswj tau - tso tawm cov ntsiav tshuaj: 400 mg / koob, ib hnub ib zaug.
Product Specifications thiab Properties
- Cov roj formula: C7H8N4O2
- Molecular Luj: 180.164
- Kub Point: 454.1 degree
- Qhov ceev: 1.465 g / cm³
- Purity: 99%
- Qhov tsos: Dawb hmoov
- Txoj Kev Tshawb Nrhiav: Kev Ua Haujlwm Siab Microspectroscopy (HPLC)
- Txheem: USP (United States Patent and Trademark Office)
Kev tsim khoom thiab kev siv
Dosage thiab Administration:
Qhov ncauj: 0.1-0.2 g / koob, ob zaug ib hnub; Qhov siab tshaj plaws koob tshuaj: 0.3 g / koob, 1 g / hnub.
Tswj tau - tso tawm cov ntsiav tshuaj: 400 mg / koob, ib hnub ib zaug.
Kev Phem Tsis Zoo
1. Kev tswj ntawm qhov ncauj yuav ua rau kub siab, xeev siab, ntuav, arrhythmia, tsis qab los noj mov, mob plab, thiab nce cov ntshav uric acid. Kev siv sij hawm ntev - yuav ua rau mob taub hau, insomnia, thiab palpitations.
2. Kev khaus khaus heev rau hauv cheeb tsam. Kev txhaj tshuaj intramuscular yuav ua rau mob hauv zos, liab, thiab o. Cov koob tshuaj yuav ua rau insomnia los yog nyob tsis tswm.
Cov kev ceev faj
Nws raug nquahu kom noj nws tom qab noj mov kom txo qis plab hnyuv. Kev haus luam yeeb, haus cawv ntev ntev, thiab ua rau cov tshuaj hepatic -metabolizing enzymes tuaj yeem ua rau txo qis theophylline plasma concentrations, yuav tsum tau nce qhov tsim nyog ntawm cov tshuaj theophylline. Theophylline tuaj yeem ua rau arrhythmias thiab ua rau arrhythmias uas twb muaj lawm; txhua qhov kev hloov hauv lub plawv dhia lossis lub suab sib dhos yuav tsum tau saib xyuas kom zoo. Kev txhaj tshuaj sai sai ntawm theophylline lossis theophylline plasma concentration ntau dua 20 ug / mL tuaj yeem ua rau muaj kev phom sij txaus ntshai, tshwm sim raws li arrhythmias, tachycardia, cov leeg tremors, qaug dab peg, tsis muaj zog hypotension, lossis peripheral circulatory tsis ua haujlwm. Thaum theophylline concentration ntau tshaj 40 ug / mL, kub taub hau, lub cev qhuav dej, thiab convulsions yuav tshwm sim. Thaum mob hnyav, nws tuaj yeem ua rau ua pa thiab mob plawv thiab tuag. Ua ntej- kev tswj hwm cov tshuaj sedative tuaj yeem tiv thaiv qhov no zoo.
Vim li cas thiaj xaiv peb:
Peb muab thawj- tes; lav kev sib tw nqi thiab zoo. Peb tuaj yeem npaj cov khoom xa tuaj tib yam - hnub tom qab koj tso qhov kev txiav txim, ua kom cov khoom zoo thiab kev xa khoom ruaj khov, ua rau peb ua tiav kev yeej- yeej kev koom tes.
